59 research outputs found

    A Rapid Emergency Deployment mobile communication node

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    In an Emergency and/or Crisis Situations (ECS) like earthquakes, floods, tsunamis, fires, terrorist attacks etc. the adequate operation of communication services is of extreme importance. History has shown that poor communication in such cases resulted in several casualties. In ECS fixed communication infrastructure might be unserviceable due to sustained damages. Evermore, the communication demand is highly increased in such cases resulting in poor quality of service as both civilians and authorities are trying to establish communications. In this paper, a Rapid Emergency Deployment mobile Communication (REDComm) node is presented. REDComm nodes include wireless communication technologies, to provide various telecommunication services in ECS and interoperability between them. It incorporates an 802.11a mesh cognitive radio technology that operates in the television broadcasting frequency bands to provide a backbone networking with increased range and flexibility. REDComm is constructed upon a trailer chassis able to minimize setup time, which is valuable in ECS. The presented platform is powered by a hybrid power source that combines thermal, solar and wind energy and eliminates the need for external power supply

    XBP1, Downstream of Blimp-1, Expands the Secretory Apparatus and Other Organelles, and Increases Protein Synthesis in Plasma Cell Differentiation

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    AbstractThe differentiation of B cells into immunoglobulin-secreting plasma cells is controlled by two transcription factors, Blimp-1 and XBP1. By gene expression profiling, we defined a set of genes whose induction during mouse plasmacytic differentiation is dependent on Blimp-1 and/or XBP1. Blimp-1-deficient B cells failed to upregulate most plasma cell-specific genes, including xbp1. Differentiating xbp1-deficient B cells induced Blimp-1 normally but failed to upregulate genes encoding many secretory pathway components. Conversely, ectopic expression of XBP1 induced a wide spectrum of secretory pathway genes and physically expanded the endoplasmic reticulum. In addition, XBP1 increased cell size, lysosome content, mitochondrial mass and function, ribosome numbers, and total protein synthesis. Thus, XBP1 coordinates diverse changes in cellular structure and function resulting in the characteristic phenotype of professional secretory cells
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